Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Mar;79(6):1781-5.
doi: 10.1073/pnas.79.6.1781.

Heat shock induces rapid dephosphorylation of a ribosomal protein in Drosophila

C V Glover

Heat shock induces rapid dephosphorylation of a ribosomal protein in Drosophila

C V Glover. Proc Natl Acad Sci U S A. 1982 Mar.

Abstract

Ribosomes isolated from Drosophila melanogaster tissue culture cells labeled in vivo with 32Pi contain a single, heavily phosphorylated, ribosomal protein. As much as 40% of this protein is phosphorylated in cells cultured at 25 degrees C. The molecular weight and other characteristics of this protein suggest possible homology with ribosomal protein S6. Following a shift-up to 37 degrees C, the protein is specifically and quantitatively dephosphorylated. The kinetics of this dephosphorylation are rapid with a half-time on the order of a few minutes. These kinetics closely parallel the heat shock-induced breakdown of the preexisting polysome population.

PubMed Disclaimer

References

    1. Arch Biochem Biophys. 1969 Mar;130(1):337-46 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. In Vitro. 1970 Nov-Dec;6(3):162-72 - PubMed
    1. Exp Cell Res. 1972 Aug;73(2):295-302 - PubMed
    1. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1379-83 - PubMed

Publication types

LinkOut - more resources