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. 1982 Jul 25;257(14):7915-7.

Site of action of a ribosomal RNA methylase conferring resistance to thiostrepton

J Thompson, F Schmidt, E Cundliffe
  • PMID: 6806287
Free article

Site of action of a ribosomal RNA methylase conferring resistance to thiostrepton

J Thompson et al. J Biol Chem. .
Free article

Abstract

A methylase enzyme, responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton. This RNA-pentose methylase modifies adenosine-1067 of Escherichia coli 23 S rRNA.

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