Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 May;131(3):255-60.
doi: 10.1007/BF00405889.

Anaerobic degradation of uric acid via pyrimidine derivatives by selenium-starved cells of Clostridium purinolyticum

P Dürre, J R Andreesen

Anaerobic degradation of uric acid via pyrimidine derivatives by selenium-starved cells of Clostridium purinolyticum

P Dürre et al. Arch Microbiol. 1982 May.

Abstract

Clostridium purinolyticum decomposed uric acid via pyrimidine derivatives under selenium starvation conditions. Products were acetate, formate, glycine, ammonia, and CO2. 4,5-Diaminouracil could be identified as an intermediate after converting the labile substance into 6,7-dimethyllumazine. The breakdown of uric acid was inhibited by EDTA. High-pressure liquid chromatography methods have been developed for the simultaneous determination of uric acid, 4,5-diaminouracil, and 6,7-dimethyllumazine. The significance of the new pathway is discussed.

PubMed Disclaimer

References

    1. Arch Microbiol. 1975;102(2):145-9 - PubMed
    1. Zentralbl Bakteriol Orig A. 1976 Aug;235(1-3):165-72 - PubMed
    1. Arch Mikrobiol. 1973 Nov 2;93(3):267-76 - PubMed
    1. J Bacteriol. 1942 Mar;43(3):291-304 - PubMed
    1. J Bacteriol. 1978 Jan;133(1):26-32 - PubMed

Publication types

LinkOut - more resources