Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Aug 21;285(6341):533-4.
doi: 10.1136/bmj.285.6341.533.

Are HLA antigens important in the development of alcohol-induced liver disease?

R Faizallah, J C Woodrow, N K Krasner, R J Walker, A I Morris

Are HLA antigens important in the development of alcohol-induced liver disease?

R Faizallah et al. Br Med J (Clin Res Ed). .

Abstract

The prevalences of 10 HLA-A and 16 HLA-B antigens were determined in 50 patients with alcoholic cirrhosis and 120 alcoholic patients without cirrhosis and compared with those in a control group of 550 healthy subjects from the same geographical area. B40 was absent in the patients with cirrhosis but was found in 18 (15%) of the patients without cirrhosis (p = 0.0087). No other association was noted. It is concluded that there is no good evidence to date of an association between HLA antigen state and susceptibility to alcohol-induced cirrhosis.

PubMed Disclaimer

References

    1. Science. 1968 Nov 8;162(3854):690-1 - PubMed
    1. Science. 1968 Mar 29;159(3822):1469-70 - PubMed
    1. Eur J Clin Invest. 1971 Sep;1(6):421-4 - PubMed
    1. Gastroenterology. 1972 Dec;63(6):1020-5 - PubMed
    1. Am J Dig Dis. 1974 Mar;19(3):199-205 - PubMed

LinkOut - more resources