Disseminated malignant phaeochromocytoma: localisation with iodine-131-labelled meta-iodobenzylguanidine
- PMID: 6812783
- PMCID: PMC1500117
- DOI: 10.1136/bmj.285.6349.1153
Disseminated malignant phaeochromocytoma: localisation with iodine-131-labelled meta-iodobenzylguanidine
Abstract
Meta-iodobenzylguanidine, a guanethidine analogue, is a newly synthesised substance capable of imaging the adrenal medulla. In a woman in whom phaeochromocytoma has been diagnosed iodine-131-labelled metaiodobenzylguanidine was given intravenously; gamma-camera images showed bilateral adrenal tumours and uptake corresponding to bone and liver metastases. 131I-meta-iodobenzylguanidine is effective in localising phaeochromocytomas, and the technique is safe, specific, and non-invasive.
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