L-Serine deaminase activity is induced by exposure of Escherichia coli K-12 to DNA-damaging agents
- PMID: 6813312
- PMCID: PMC221519
- DOI: 10.1128/jb.152.2.702-705.1982
L-Serine deaminase activity is induced by exposure of Escherichia coli K-12 to DNA-damaging agents
Abstract
The synthesis of L-serine deaminase in Escherichia coli K-12 was induced after exposure of cells to a variety of DNA-damaging agents, including UV irradiation, nalidixic acid, and mitomycin C. Synthesis was also induced during growth at high temperature. A mutant constitutive for SOS functions showed an elevated level of L-serine deaminase activity. The response to DNA-damaging agents thus may be mediated via the SOS system.
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