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. 1982 Nov;152(2):702-5.
doi: 10.1128/jb.152.2.702-705.1982.

L-Serine deaminase activity is induced by exposure of Escherichia coli K-12 to DNA-damaging agents

L-Serine deaminase activity is induced by exposure of Escherichia coli K-12 to DNA-damaging agents

E B Newman et al. J Bacteriol. 1982 Nov.

Abstract

The synthesis of L-serine deaminase in Escherichia coli K-12 was induced after exposure of cells to a variety of DNA-damaging agents, including UV irradiation, nalidixic acid, and mitomycin C. Synthesis was also induced during growth at high temperature. A mutant constitutive for SOS functions showed an elevated level of L-serine deaminase activity. The response to DNA-damaging agents thus may be mediated via the SOS system.

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