Comparative studies on spontaneous and mitomycin-C-induced sister-chromatid exchanges in smokers and non-smokers
- PMID: 6815523
- DOI: 10.1016/0165-7992(82)90011-2
Comparative studies on spontaneous and mitomycin-C-induced sister-chromatid exchanges in smokers and non-smokers
Abstract
Both spontaneous and mitomycin-C-induced sister-chromatid exchanges were analyzed in 6 smokers and 6 non-smokers. The average number of spontaneous SCE in smokers' cells was 8.33 +/- 1.08. The frequency in the non-smoking controls was 4.41 +/- 0.72. This difference is highly significant (P less than 0.001). Smokers also had more SCE at all levels of mitomycin C testes. Analysis of variance showed these differences to be highly significant (P less than 0.001).
Similar articles
-
In vivo and in vitro effects of cigarette smoke on chromosomal damage and sister-chromatid exchange in human peripheral blood lymphocytes.Mutat Res. 1982 Feb 22;92(1-2):321-32. doi: 10.1016/0027-5107(82)90234-2. Mutat Res. 1982. PMID: 7088010
-
Effects of smoking on spontaneous and induced sister chromatid exchanges in lymphocytes.Toxicol Lett. 1985 Jun;25(3):293-6. doi: 10.1016/0378-4274(85)90210-3. Toxicol Lett. 1985. PMID: 3925600
-
Spontaneous and mutagen induced sister chromatid exchange in multiple sclerosis.J Med Genet. 1983 Oct;20(5):372-6. doi: 10.1136/jmg.20.5.372. J Med Genet. 1983. PMID: 6417337 Free PMC article.
-
Apparent enhanced response to the induction of sister chromatid exchange by mitomycin C in myotonic dystrophy.J Med Genet. 1982 Apr;19(2):135-8. doi: 10.1136/jmg.19.2.135. J Med Genet. 1982. PMID: 6804630 Free PMC article.
-
Sister chromatid exchanges in lymphocytes of cancer patients receiving mitomycin C treatment.Cancer Res. 1980 Feb;40(2):477-80. Cancer Res. 1980. PMID: 7356530
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources