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Comparative Study
. 1982 Sep;105(3):195-200.
doi: 10.1016/0165-7992(82)90011-2.

Comparative studies on spontaneous and mitomycin-C-induced sister-chromatid exchanges in smokers and non-smokers

M Cui, J Xu, X Zhou
Comparative Study

Comparative studies on spontaneous and mitomycin-C-induced sister-chromatid exchanges in smokers and non-smokers

M Cui et al. Mutat Res. 1982 Sep.

Abstract

Both spontaneous and mitomycin-C-induced sister-chromatid exchanges were analyzed in 6 smokers and 6 non-smokers. The average number of spontaneous SCE in smokers' cells was 8.33 +/- 1.08. The frequency in the non-smoking controls was 4.41 +/- 0.72. This difference is highly significant (P less than 0.001). Smokers also had more SCE at all levels of mitomycin C testes. Analysis of variance showed these differences to be highly significant (P less than 0.001).

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