Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1982 Dec;14(6):805-8.
doi: 10.1111/j.1365-2125.1982.tb02040.x.

A placebo controlled study of the cardiovascular effects of fluvoxamine and clovoxamine in human volunteers

J F Robinson, D P Doogan
Clinical Trial

A placebo controlled study of the cardiovascular effects of fluvoxamine and clovoxamine in human volunteers

J F Robinson et al. Br J Clin Pharmacol. 1982 Dec.

Abstract

1 Fluvoxamine and clovoxamine, two new potential antidepressants were given to 27 healthy male volunteers in a double-blind, placebo controlled, three-way crossover study. 2 Neither compound affected the electrical intervals of 24 h ambulant electrocardiographic monitoring with the exception of a small increase in R-R interval. 3 There were no changes in blood pressure measurements. 4 The only notable unwanted symptom was nausea for both fluvoxamine and clovoxamine.

PubMed Disclaimer

References

    1. Br J Pharmacol. 1977 Aug;60(4):505-16 - PubMed
    1. J Neural Transm. 1977;41(1):17-36 - PubMed
    1. Br J Clin Pharmacol. 1978;5 Suppl 1:19S-20S - PubMed
    1. Eur J Pharmacol. 1979 Aug 15;57(4):335-42 - PubMed
    1. Postgrad Med J. 1979 Oct;55(648):704-8 - PubMed

Publication types