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Clinical Trial
. 1982 Dec;54(6):780-4.
doi: 10.1111/j.1464-410x.1982.tb13647.x.

Randomised trial of clomiphene citrate treatment and vitamin C for male infertility

B J Abel, G Carswell, R Elton, T B Hargreave, K Kyle, S Orr, A Rogers, K Baxby, A Yates
Clinical Trial

Randomised trial of clomiphene citrate treatment and vitamin C for male infertility

B J Abel et al. Br J Urol. 1982 Dec.

Abstract

A prospective randomised trial was carried out to assess the effect of 6 months' treatment with either clomiphene citrate or vitamin C in 179 men complaining of infertile marriage. There was no significant difference in the wife's pregnancy rates between the 2 treatment groups. In order to detect a subgroup that might respond to clomiphene the results were analysed according to pre-treatment FSH and sperm density, with allowance being made for the result of the wife's tests, but still there was no significant difference in treatment response Vitamin C would seem a preferable and cheaper alternative treatment for male infertility.

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