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. 1982 Dec;79(24):7809-13.
doi: 10.1073/pnas.79.24.7809.

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization

J M Trent et al. Proc Natl Acad Sci U S A. 1982 Dec.

Abstract

Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-alpha), fibroblast interferon (IFN-beta), or immune interferon (INF-gamma) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN-alpha and IFN-beta genes to the short arm of chromosome 9(p21-->pter) and localized the IFN-gamma gene to the long arm of chromosome 12(q24.1).

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