Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization
- PMID: 6818550
- PMCID: PMC347438
- DOI: 10.1073/pnas.79.24.7809
Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization
Abstract
Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-alpha), fibroblast interferon (IFN-beta), or immune interferon (INF-gamma) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN-alpha and IFN-beta genes to the short arm of chromosome 9(p21-->pter) and localized the IFN-gamma gene to the long arm of chromosome 12(q24.1).
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