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Review
. 1982 Nov-Dec;4(6):1133-53.
doi: 10.1093/clinids/4.6.1133.

Clindamycin: a review of fifteen years of experience

V K Dhawan, H Thadepalli
Review

Clindamycin: a review of fifteen years of experience

V K Dhawan et al. Rev Infect Dis. 1982 Nov-Dec.

Abstract

Clindamycin, the 7(S)-chloro-7-deoxy derivative of lincomycin, has stood the test of time in the treatment of anaerobic infections. Clindamycin inhibits protein synthesis by acting on the 50S ribosomal subunits of bacteria. The colitis resulting from the use of clindamycin has been extensively studied and is now easily manageable. Although newer antibiotics active against anaerobes are available, clindamycin remains a reliable and well-tested antibiotic for use in anaerobic infections.

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