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. 1978 Aug;41(8):699-701.
doi: 10.1136/jnnp.41.8.699.

Histocompatibility antigens (HLA) in multiple sclerosis in Iran

J Lotfi, B Nikbin, I Derakhshan, Z Aghai, F Ala

Histocompatibility antigens (HLA) in multiple sclerosis in Iran

J Lotfi et al. J Neurol Neurosurg Psychiatry. 1978 Aug.

Abstract

Thirty-five patients (19 male and 16 female) with clinically definite multiple sclerosis and 100 healthy control subjects were studied for the A and B locus of the HLA system. A significant increase of HLA A3 and A11 of the A locus and B7 of the B locus was observed in patients with multiple sclerosis compared with controls. An increase of antigen A3 was also observed in eight cases of probable multiple sclerosis. A significant increase of both A3 and B7 was observed in patients with multiple sclerosis.

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