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Clinical Trial
. 1983 Jan 1;51(1):57-60.
doi: 10.1002/1097-0142(19830101)51:1<57::aid-cncr2820510114>3.0.co;2-v.

Corynebacterium parvum versus BCG adjuvant immunotherapy in human malignant melanoma

A Lipton, H A Harvey, B Lawrence, R Gottlieb, M Kukrika, R Dixon, W Graham, S Miller, R Heckard, D Schelzel, D S White
Clinical Trial

Corynebacterium parvum versus BCG adjuvant immunotherapy in human malignant melanoma

A Lipton et al. Cancer. .

Abstract

One-hundred and sixteen patients with Stage I and Stage II malignant melanoma were randomized to treatment with either Bacillus Calmette-Guerin (BCG) (Tice) or subcutaneous Corynebacterium parvum (Burroughs-Wellcome). Life table analysis failed to reveal a difference between these two forms of treatment in 68 Stage I patients. The relapse rate was significantly reduced in Stage II patients treated with C. parvum.

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