Killing of blood-stage murine malaria parasites by hydrogen peroxide
- PMID: 6822428
- PMCID: PMC347962
- DOI: 10.1128/iai.39.1.456-459.1983
Killing of blood-stage murine malaria parasites by hydrogen peroxide
Abstract
Both nonlethal Plasmodium yoelii and lethal Plasmodium berghei were killed in vitro by hydrogen peroxide at concentrations as low as 10(-5) M. Higher concentrations were required in the presence of added normal erythrocytes. Injection of hydrogen peroxide in vivo significantly reduced P. yoelii parasitemia but had less effect on P. berghei.
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