doi: 10.1126/science.6823571.
Free-running activity rhythms in the rat: entrainment by melatonin
- PMID: 6823571
- DOI: 10.1126/science.6823571
Item in Clipboard
Free-running activity rhythms in the rat: entrainment by melatonin
Science.
.
Abstract
The pineal gland hormone melatonin may play a role in synchronization of rat circadian rhythms. Free-running activity rhythms of the rat were entrained by a daily melatonin injection, with entrainment occurring when the onset of activity coincided with the time of daily injections. When injections were stopped, activity rhythms became free-running again. Thus in pharmacological experiments, the time of day of melatonin administration is crucial.
Similar articles
-
Melatonin administration: effects on rodent circadian rhythms.Ciba Found Symp. 1985;117:188-207. doi: 10.1002/9780470720981.ch12. Ciba Found Symp. 1985. PMID: 3836814
-
Entrainment of rat circadian rhythms by the melatonin agonist S-20098 requires intact suprachiasmatic nuclei but not the pineal.J Biol Rhythms. 1998 Feb;13(1):39-51. doi: 10.1177/074873098128999907. J Biol Rhythms. 1998. PMID: 9486842
-
Circadian rhythms in lizards: phase response curve for melatonin.J Pineal Res. 1986;3(2):187-96. doi: 10.1111/j.1600-079x.1986.tb00741.x. J Pineal Res. 1986. PMID: 3723331
-
Melatonin and circadian control in mammals.Experientia. 1989 Oct 15;45(10):932-8. doi: 10.1007/BF01953050. Experientia. 1989. PMID: 2680573 Review.
-
Melatonin, the pineal gland, and circadian rhythms.J Biol Rhythms. 1993;8 Suppl:S73-81. J Biol Rhythms. 1993. PMID: 8274765 Review.
Cited by
-
Sleep timing and the circadian clock in mammals: Past, present and the road ahead.Semin Cell Dev Biol. 2022 Jun;126:3-14. doi: 10.1016/j.semcdb.2021.05.034. Epub 2021 Jun 4. Semin Cell Dev Biol. 2022. PMID: 34092510 Free PMC article. Review.
-
Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats.Br J Pharmacol. 2005 Sep;146(1):33-40. doi: 10.1038/sj.bjp.0706311. Br J Pharmacol. 2005. PMID: 15980870 Free PMC article.
-
CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access.J Neurosci. 1998 Dec 15;18(24):10389-97. doi: 10.1523/JNEUROSCI.18-24-10389.1998. J Neurosci. 1998. PMID: 9852576 Free PMC article.
-
From the Pineal Gland to the Central Clock in the Brain: Beginning of Studies of the Mammalian Biological Rhythms in the Institute of Physiology of the Czech Academy of Sciences.Physiol Res. 2024 May 31;73(Suppl 1):S1-S21. doi: 10.33549/physiolres.935377. Epub 2024 May 31. Physiol Res. 2024. PMID: 38836462 Free PMC article. Review.
-
Circadian rhythm in melatonin release as a mechanism to reinforce the temporal organization of the circadian system in crayfish.Invert Neurosci. 2017 Jun;17(2):6. doi: 10.1007/s10158-017-0199-6. Epub 2017 May 24. Invert Neurosci. 2017. PMID: 28540583
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
