Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1983 Jan;78(1):5-7.
doi: 10.1111/j.1476-5381.1983.tb09355.x.

A comparison of some of the properties of the [3H]-sulpiride binding site in soluble and native membrane preparations of dog striatum

W W Templeton, G N Woodruff
Comparative Study

A comparison of some of the properties of the [3H]-sulpiride binding site in soluble and native membrane preparations of dog striatum

W W Templeton et al. Br J Pharmacol. 1983 Jan.

Abstract

[3H]-sulpiride binding sites in dog striatum have been solubilised using CHAPS detergent. Solubilised sites were similar to those in native membrane preparations in terms of Bmax, Kd and sensitivity to dopamine and dopamine receptor antagonists. Binding of [3H]-sulpiride to the solubilised binding site was dependent upon the presence of sodium ions and was inactivated by the sulphydryl group reagent N-ethylmaleimide.

PubMed Disclaimer

References

    1. Biochem Pharmacol. 1973 Dec 1;22(23):3099-108 - PubMed
    1. J Pharm Pharmacol. 1980 Jun;32(6):441-4 - PubMed
    1. Neuroscience. 1981;6(3):407-10 - PubMed
    1. Eur J Pharmacol. 1981 Jul 10;72(4):403-5 - PubMed
    1. Neuropharmacology. 1981 Dec;20(12B):1323-6 - PubMed

Publication types

LinkOut - more resources