Laminar distributions of 2-deoxyglucose uptake in the rat spinal cord following electrical stimulation of the sciatic nerve

Abstract

The 2-deoxyglucose method was employed to study the functional organization of afferent axons in the dorsal horn of the rat spinal cord. Stimulation of axons in the sciatic nerve with conduction velocities greater than 17 m/s produced activity predominantly in the deep laminae of the dorsal horn. In contrast, stimulation of the entire population produced activity throughout the dorsal horn. The results are discussed in relation to the functional organization of the rat dorsal horn.