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Case Reports
. 1983 Jan;129(1):143-4.
doi: 10.1016/s0022-5347(17)51964-3.

Urothelial carcinoma after cyclophosphamide therapy

Case Reports

Urothelial carcinoma after cyclophosphamide therapy

S M Moinuddin et al. J Urol. 1983 Jan.

Abstract

We report a case of transitional cell carcinoma of the bladder after cyclophosphamide therapy for chronic lymphocytic leukemia. Urologic evaluation and histologic confirmation occurred only after low grade tumor cells were identified in multiple urine samples. Malignant cells can be distinguished from drug effect in urinary specimens from patients treated with cyclophosphamide and all such cases should include regular cytologic evaluations.

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