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. 1983 Jan;5(1):67-76.
doi: 10.1111/j.1365-3024.1983.tb00724.x.

Site of expression of immunity to Naegleria fowleri in immunized mice

Y H Thong, R F Carter, A Ferrante, B Rowan-Kelly

Site of expression of immunity to Naegleria fowleri in immunized mice

Y H Thong et al. Parasite Immunol. 1983 Jan.

Abstract

An experiment was performed which confirmed a previous finding that mice are protected against Naegleria fowleri infection by immunization with amoeba-free supernatant from amoeba cultures. Histological observations suggested that this protection is expressed mainly at the nasal mucosa and possibly results from the combined effects of polymorphonuclear leucocyte-mediated killing of the amoeba and mechanical elimination of the organisms by extensive shedding of necrotic epithelium.

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