Color coded triarylmethyl protecting groups useful for deoxypolynucleotide synthesis
- PMID: 6828388
- PMCID: PMC325818
- DOI: 10.1093/nar/11.5.1589
Color coded triarylmethyl protecting groups useful for deoxypolynucleotide synthesis
Abstract
Triarylmethyl groups having different colors but similar chemical reactivities in acid were examined as potential aids for monitoring the stepwise addition of mononucleotides to a deoxyoligonucleotide. The successful application of these protecting groups to deoxyoligonucleotide synthesis on polymer supports was demonstrated.
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