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. 1983 Apr 15;39(4):369-71.
doi: 10.1007/BF01963127.

Demonstration of vascular redistribution after carotid clamping in rats

P Lespinasse, M Le Poncin-Lafitte, P C Pesquies, J R Rapin

Demonstration of vascular redistribution after carotid clamping in rats

P Lespinasse et al. Experientia. .

Abstract

In Long Evans rats, the vertebral arteries supply only the brain stem. Simultaneous application of clamps to both carotid arteries results in a considerable fall of cerebral blood flow and eventually death. If an interval of about 4 days is allowed between the clamping of the 2 carotids, redistribution of blood flow takes place. Owing to this mechanism, 50% of the rats survive with a satisfactory restoration of cerebral blood flow.

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