Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983;105(1):20-3.
doi: 10.1007/BF00391826.

Estimation of liver tumor volume using different formulas - an experimental study in rats

G Carlsson, B Gullberg, L Hafström

Estimation of liver tumor volume using different formulas - an experimental study in rats

G Carlsson et al. J Cancer Res Clin Oncol. 1983.

Abstract

Experimental solitary ellipsoid liver tumors in the rat can be induced by inoculation of a tumor-cell suspension of known potency into the liver parenchyma. During laparotomy, the largest (a) and the smallest (b) superficial diameters of the tumor were measured on the surface of the liver with vernier calipers. Four different formulas have been tested and compared with the actual volume from the extirpated tumor and tumor weight. Within the size range of 15-700 mm3, based on the calculation of the difference between logarithmic tumor volume from the different formulas versus logarithmic volume of extirpated and dissected tumors and regression analyses, volume of the unremoved liver tumor can be best calculated according to the formula V = a x b2/2.

PubMed Disclaimer

References

    1. Begg AC (1971) Kinetic and histological changes of serially transplanted mouse tumor. Cell Tissue Kinet 4:401–411 - PubMed
    1. Boyse EA, Old LJ, Thomas G (1962) A report on some observations with a simplified cytotoxic test. Transplant Bull 29:63–67 - PubMed
    1. Brues AM, Weiner AE, Andervont HB (1939) Relation between latent period and growth rate in chemically induced tumors. Proc Soc Exp Biol Med 42:374–377
    1. Chambers H, Scott GM (1930) Variations in the growth of the Jensen rat sarcoma and the influence of technique. J Pathol Bacteriol 33:553–561
    1. Dethlefsen LA, Prewitt JMS, Mendelsohn ML (1968) Analysis of tumor growth curves. J Natl Cancer Inst 40:389–405 - PubMed

Publication types

LinkOut - more resources