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. 1983 Feb;21(1-2):123-33.

Electrophoretic characterization and genetics of human biliverdin reductase (BLVR; EC 1.3.1.24); assignment of BLVR to the p14 leads to cen region of human chromosome 7 in mouse-human somatic cell hybrids

P Meera Khan, L M Wijnen, J T Wijnen, K H Grzeschik
  • PMID: 6838484

Electrophoretic characterization and genetics of human biliverdin reductase (BLVR; EC 1.3.1.24); assignment of BLVR to the p14 leads to cen region of human chromosome 7 in mouse-human somatic cell hybrids

P Meera Khan et al. Biochem Genet. 1983 Feb.

Abstract

A simple chromogenic staining procedure is described for the specific identification of biliverdin reductase (BLVR) after gel electrophoresis. Using this procedure a gene for BLVR was assigned to the p14 leads to cen region of human chromosome 7 in human-mouse somatic cell hybrids. Incidentally, the study indicated that the NADH-as well as the NADPH-dependent BLVR activities are due to one and the same enzyme and that, most probably, only one gene in the human genome codes for BLVR and the BLVR is a monomer in its functional configuration.

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References

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