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Clinical Trial
. 1983 Jan;27(1):75-84.
doi: 10.1016/0010-7824(83)90058-6.

A randomised comparative evaluation of the copper 7, multiload copper 250 and T copper-22OC IUDs

T H Goh, T A Sinnathuray, V Sivanesaratnam, D K Sen, L S Lim, S S Ratnam, S M Karim, T McCarthy, H Hutapea, M J Hanafiah, P Simandjuntak
Clinical Trial

A randomised comparative evaluation of the copper 7, multiload copper 250 and T copper-22OC IUDs

T H Goh et al. Contraception. 1983 Jan.

Abstract

Two new Cu-IUDs, the TCu-22OC and Multiload Cu250, were evaluated against the Cu7 in 1,199 subjects in a randomised, multicentric trial using a common study protocol. During the 2 years following insertion, cumulative first-segment rates for total use-related terminations showed no significant differences between the 3 devices; however, the Cu7 had a significantly higher termination rate for accidental pregnancy compared to the TCu-22OC and its expulsion rate was significantly higher than the ML Cu250. The rate of accidental pregnancy was higher and the expulsion rate lower with the ML Cu250 compared to the TCu-22OC but these differences were not significant. The results are discussed in relation to IUD design and their application in family planning.

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