Combined treatment of autochthonous 3-methylcholanthrene-induced murine tumors by immunotherapy and radiotherapy
- PMID: 6840433
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Combined treatment of autochthonous 3-methylcholanthrene-induced murine tumors by immunotherapy and radiotherapy
Gan.
1983 Feb.
Abstract
C57BL/6J mice with autochthonous 3-methylcholanthrene-induced tumors were given combined therapy with 2,000 rad of local irradiation and regional injections of cell-wall skeleton of Nocardia rubra (N-CWS). The greatest suppression of the tumor growth and the highest survival rate were observed in the combined treatment group as compared to the non-treated control, regional injections of N-CWS alone and irradiation alone groups. In addition, pulmonary metastasis was significantly suppressed by the combined therapy.
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