Relation between discharges in auditory nerve fibers and the whole-nerve response shown by forward masking: an empirical model for the AP

Abstract

Whole-nerve action potentials evoked by a standard click were recorded from a gross electrode on the RW and the discharges of auditory nerve fibers to the same standard click were recorded from micropipette electrodes in the auditory nerve. The effect of a preceding tone burst (2, 4, or 8 kHz) upon the responses was measured for forward-masker intensities from 20 to 80 dB SPL. All forward maskers reduced the discharges of auditory nerve fibers to the standard click with the greatest reduction occurring for fibers with characteristic frequencies (CFs) near the masker frequency. The 4- and 8-kHz forward maskers produced similar effects on N1, P1, and N2 of the RW response. However, the 2-kHz forward masker produced enhancement at P1 and N2 in the RW response to the standard click. An empirical summation model of estimated elemental waveforms at latencies dependent on CF produces synthesized AP response waveforms which are similar to the observed RW response. The model permits the exclusion of discharges from segments along the cochlear partition in a manner similar to the effect of a forward masker. Alterations in the synthesized waveforms due to the exclusion of segments are similar in direction to the alterations observed in the RW responses for forward masking.