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Case Reports
. 1983 Feb;46(2):183-5.
doi: 10.1136/jnnp.46.2.183.

Cerebellar syndrome following neuroleptic induced heat stroke

D Lefkowitz, C S Ford, C Rich, J Biller, L C McHenry Jr
Case Reports

Cerebellar syndrome following neuroleptic induced heat stroke

D Lefkowitz et al. J Neurol Neurosurg Psychiatry. 1983 Feb.

Abstract

We report a patient in whom extreme hyperthermia, rhabdomyolysis, acute renal failure and a residual pancerebellar syndrome occurred while taking a combination of perphenazine and amitriptyline. We postulate that impaired thermoregulation due to psychotropic drugs was responsible for the development of heat stroke and that the cerebellar syndrome resulted directly from the elevated temperature.

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