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Case Reports
. 1983 Feb;140(2):203-5.
doi: 10.1176/ajp.140.2.203.

Abnormal cortisol suppression in bipolar patients with simultaneous manic and depressive symptoms

Case Reports

Abnormal cortisol suppression in bipolar patients with simultaneous manic and depressive symptoms

R R Krishnan et al. Am J Psychiatry. 1983 Feb.

Abstract

The authors studied the cortisol response to 1 mg of dexamethasone in 10 patients who simultaneously manifested manic and depressive symptoms. All patients showed some evidence that normal cortisol suppression was lacking. When 3 patients were randomly retested after recovery, the results suggested the normalization of suppression.

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