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. 1983 Apr;7(4):257-61.
doi: 10.1016/0309-1651(83)90059-0.

Enhanced 5-hydroxytryptamine sensitivity of morphologically differentiated neuroblastoma cells

F Guharay

Enhanced 5-hydroxytryptamine sensitivity of morphologically differentiated neuroblastoma cells

F Guharay. Cell Biol Int Rep. 1983 Apr.

Abstract

The addition of 2% (vol./vol.) dimethyl sulfoxide to replated confluent cultures of NIE-115 neuroblastoma cells abolishes cell-proliferation and induces extensive neurite formation. The morphologically differentiated cells exhibit higher resting membrane potential and higher input resistance. In addition the differentiated cells also express an increased sensitivity to 5-hydroxytryptamine.

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