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. 1983 Jun 10;220(4602):1173-5.
doi: 10.1126/science.6857241.

Hemoglobin aggregation in single red blood cells of sickle cell anemia

I Nishio, T Tanaka, S T Sun, Y Imanishi, S T Ohnishi

Hemoglobin aggregation in single red blood cells of sickle cell anemia

I Nishio et al. Science. .

Abstract

A laser light scattering technique was used to observe the extent of hemoglobin aggregation in solitary red blood cells of sickle cell anemia. Hemoglobin aggregation was confirmed in deoxygenated cells. The light scattering technique can also be applied to cytoplasmic studies of any biological cell.

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