Inhibition of tumor promotion by a biomimetic superoxide dismutase
- PMID: 6857269
- DOI: 10.1126/science.6857269
Inhibition of tumor promotion by a biomimetic superoxide dismutase
Abstract
A low molecular weight, lipophilic, copper coordination complex with superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.
Similar articles
-
Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic superoxide dismutase.Carcinogenesis. 1990 May;11(5):749-54. doi: 10.1093/carcin/11.5.749. Carcinogenesis. 1990. PMID: 2110512
-
Effects of a biomimetic superoxide dismutase on complete and multistage carcinogenesis in mouse skin.Carcinogenesis. 1985 Aug;6(8):1167-72. doi: 10.1093/carcin/6.8.1167. Carcinogenesis. 1985. PMID: 3926337
-
The study of tumor promotion in a cell culture model for mouse skin--a tissue that exhibits multistage carcinogenesis in vivo.Carcinog Compr Surv. 1982;7:217-30. Carcinog Compr Surv. 1982. PMID: 6121622 No abstract available.
-
Specificity and mechanism(s) of promoter inhibitors in multistage promotion.Carcinog Compr Surv. 1982;7:19-34. Carcinog Compr Surv. 1982. PMID: 7039828 Review. No abstract available.
-
Mouse skin: a useful model system for studying the mechanism of chemical carcinogenesis.Carcinog Compr Surv. 1982;7:1-12. Carcinog Compr Surv. 1982. PMID: 6802487 Review.
Cited by
-
Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation and reactive oxygen formation by bile acids.J Clin Invest. 1987 Feb;79(2):532-41. doi: 10.1172/JCI112844. J Clin Invest. 1987. PMID: 3027128 Free PMC article.
-
Purification of an inhibitor of erythroid progenitor cell cycling and antagonist to interleukin 3 from mouse marrow cell supernatants and its identification as cytosolic superoxide dismutase.J Cell Biol. 1990 Sep;111(3):1217-23. doi: 10.1083/jcb.111.3.1217. J Cell Biol. 1990. PMID: 2391363 Free PMC article.
-
Phorbol ester inhibits phosphatidylserine synthesis in human promyelocytic leukaemia HL60 cells. Possible involvement of free radicals and correlation with phosphorylation of nuclear protein 1b.Biochem J. 1987 Dec 15;248(3):649-56. doi: 10.1042/bj2480649. Biochem J. 1987. PMID: 3435475 Free PMC article.
-
Serum activity and hepatic localization of superoxide dismutase in alcoholics.Gastroenterol Jpn. 1989 Jun;24(3):277-83. doi: 10.1007/BF02774325. Gastroenterol Jpn. 1989. PMID: 2663607
-
Long-term follow-up study of changes in lipid peroxide levels and the activity of superoxide dismutase, catalase and glutathione peroxidase in mouse skin after acute and chronic UV irradiation.Arch Dermatol Res. 1994;286(1):47-52. doi: 10.1007/BF00375843. Arch Dermatol Res. 1994. PMID: 8141612
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources