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. 1983 Jul 1;221(4605):75-7.
doi: 10.1126/science.6857269.

Inhibition of tumor promotion by a biomimetic superoxide dismutase

Inhibition of tumor promotion by a biomimetic superoxide dismutase

T W Kensler et al. Science. .

Abstract

A low molecular weight, lipophilic, copper coordination complex with superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.

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