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. 1983 Jun;42(3):297-300.
doi: 10.1136/ard.42.3.297.

Evidence for an association between rheumatoid arthritis and autoimmune endocrine disease

D J Thomas, A Young, A N Gorsuch, G F Bottazzo, A G Cudworth

Evidence for an association between rheumatoid arthritis and autoimmune endocrine disease

D J Thomas et al. Ann Rheum Dis. 1983 Jun.

Abstract

Evidence is presented for the first time of a significantly increased prevalence of type 1 (insulin-dependent) diabetes in the close relatives of patients with rheumatoid arthritis. Thirty-nine (13%) of 295 patients with classical or definite rheumatoid arthritis had a first or second degree relative with type 1 diabetes and 38 (13%) had a close relative with autoimmune thyroid disease. These findings could be compatible with a possible common genetically determined mechanism of susceptibility to both diseases.

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