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. 1983 Apr;29(2):259-64.
doi: 10.1016/0006-2944(83)90046-7.

In vitro absorption of [14C]leucine during inflammation and the effect of antiinflammatory drugs in the jejunum of rats

In vitro absorption of [14C]leucine during inflammation and the effect of antiinflammatory drugs in the jejunum of rats

S Somasundaram et al. Biochem Med. 1983 Apr.

Abstract

1. Inflammation was induced in the hindlegs of rats by formalin injection and the in vitro absorption of [14C]leucine was studied. 2. Treatment of rats with formalin caused a reduction in the in vitro absorption of leucine from the mucosa of jejunum. 3. Oral administration of oxyphenbutazone or a herbal anti-inflammatory drug (Withania somnifera) prior to formalin injection resulted in no alteration in the jejunal absorption of [14C]leucine.

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