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. 1983;8(1):77-84.
doi: 10.1007/BF03189584.

Identification of the major urinary metabolites of (+)-catechin and 3-O-methyl-(+)-catechin in man

Identification of the major urinary metabolites of (+)-catechin and 3-O-methyl-(+)-catechin in man

M Wermeille et al. Eur J Drug Metab Pharmacokinet. 1983.

Abstract

Following oral administration of (+)-catechin and 3-O-methyl-(+)-catechin to human volunteers the major urinary metabolites were shown to be the glucuronides of 3'-O-methyl-(+)-catechin respectively. Isolations from urine and from synthetic products have been carried out by semi-preparative high performance liquid chromatography; definitive elucidations of structures have been carried out by gas chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy.

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