Quantitative assessment of carbon tetrachloride levels in human blood by head-space gas chromatography: application in a case of suicidal carbon tetrachloride intoxication
- PMID: 6863723
- DOI: 10.1007/BF01772580
Quantitative assessment of carbon tetrachloride levels in human blood by head-space gas chromatography: application in a case of suicidal carbon tetrachloride intoxication
Abstract
A head-space gas chromatographic method for the determination of carbon tetrachloride in human blood is described. Standard samples with 0.5 ml whole blood containing different concentrations of CCl4 were analyzed at column temperatures ranging from 50 degrees to 90 degrees C. Advantages of this method include high sensitivity, simplicity in handling, rapid achievement of reliable results, accuracy and low costs. The practicability of this analytical method was studied in a patient following suicidal oral ingestion of a lethal dose of carbon tetrachloride.
Similar articles
-
[Gas chromatographic determination of carbon tetrachloride in the air and in blood].Gig Sanit. 1971 Dec;36(12):58-61. Gig Sanit. 1971. PMID: 5145693 Russian. No abstract available.
-
Two rapid methods for the simultaneous gas-liquid chromatographic determination of carbon tetrachloride and chloroform in biological material and expired air.J Chromatogr. 1980 May 16;193(1):71-82. doi: 10.1016/s0021-9673(00)81445-4. J Chromatogr. 1980. PMID: 7391206
-
[Carbon tetrachloride poisoning. Dynamic relations between serum lipids and CC14 concentration in blood and fatty tissue].Z Gesamte Hyg. 1980;26(6):421-5. Z Gesamte Hyg. 1980. PMID: 7405282 German. No abstract available.
-
Carbon tetrachloride (CCl4) levels and serum activities of liver enzymes following acute CCl4 intoxication.Toxicol Lett. 1983 Jun;17(1-2):175-80. doi: 10.1016/0378-4274(83)90054-1. Toxicol Lett. 1983. PMID: 6623503
-
Hyperbaric oxygen treatment for carbon tetrachloride poisoning.Drug Saf. 1991 Sep-Oct;6(5):332-8. doi: 10.2165/00002018-199106050-00003. Drug Saf. 1991. PMID: 1930739 Review.
Cited by
-
Liver Injury by Carbon Tetrachloride Intoxication in 16 Patients Treated with Forced Ventilation to Accelerate Toxin Removal via the Lungs: A Clinical Report.Toxics. 2018 Apr 27;6(2):25. doi: 10.3390/toxics6020025. Toxics. 2018. PMID: 29702608 Free PMC article. Review.
-
Effect of CO2-induced hyperventilation on carbon tetrachloride (CCl4) levels following acute CCl4 poisoning.Intensive Care Med. 1983;9(6):333-7. doi: 10.1007/BF01692552. Intensive Care Med. 1983. PMID: 6418782
-
Effect of ethanol on carbon tetrachloride levels and hepatotoxicity after acute carbon tetrachloride poisoning.Arch Toxicol. 1984 Dec;56(2):78-82. doi: 10.1007/BF00349075. Arch Toxicol. 1984. PMID: 6532381
-
Aliphatic Halogenated Hydrocarbons: Report and Analysis of Liver Injury in 60 Patients.J Clin Transl Hepatol. 2018 Dec 28;6(4):350-361. doi: 10.14218/JCTH.2018.00040. Epub 2018 Nov 16. J Clin Transl Hepatol. 2018. PMID: 30637211 Free PMC article.
-
Protective effects of Baccharis dracunculifolia leaves extract against carbon tetrachloride- and acetaminophen-induced hepatotoxicity in experimental animals.Molecules. 2014 Jul 2;19(7):9257-72. doi: 10.3390/molecules19079257. Molecules. 2014. PMID: 24991758 Free PMC article.