Bunyavirus gene structure - function relationships and potential for RNA segment reassortment in the vector: La Crosse and snowshoe hare reassortant viruses in mosquitoes

Abstract

Modern technology now permits the elucidation of viral gene contributions to virus-vector interactions. Such knowledge will undoubtedly permit determination of those mechanisms which function to preserve vector-borne virus disease cycle specificity and integrity in nature. In addition, the application of genetic techniques to reassortant virus generation in vectors should permit prediction of the evolutionary and epidemic potential of viruses in nature.