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. 1978 Aug;37(4):366-9.
doi: 10.1136/ard.37.4.366.

Neutropenia during treatment of rheumatoid arthritis with levamisole

G T Williams, S A Johnson, P A Dieppe, E C Huskisson

Neutropenia during treatment of rheumatoid arthritis with levamisole

G T Williams et al. Ann Rheum Dis. 1978 Aug.

Abstract

Of 60 patients with rheumatoid arthritis treated with levamisole 35% showed a persistent decrease in neutrophil counts from pre-treatment levels and 6 (10%) develped severe neutropenia of less than 1.0 X 10(9)/1. One of these neutropenic patients recoverd without stopping therapy and the other 5 patients recovered rapidly when the drug was withdrawn. In some patients neutropenia recurred on reinstitution of levamisole.

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