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. 1983 Apr;237(3):273-7.
doi: 10.1007/BF00453732.

Intracellular and extracellular ion content of the endolymphatic sac

H Amano, A Orsulakova, C Morgenstern

Intracellular and extracellular ion content of the endolymphatic sac

H Amano et al. Arch Otorhinolaryngol. 1983 Apr.

Abstract

The Cl- activity in the endolymph of the endolymphatic sac and in the cochlear duct was measured with Cl- sensitive double-barreled microelectrodes. The Cl- activity in the endolymphatic sac fluid was lower than in the cochlear duct. A small, positive, DC potential was recorded in the endolymphatic sac. During anoxia, the DC potential decreased while the Cl- activity in the endolymphatic sac increased. The K/Na ratio in the epithelial cells and subepithelial tissue of endolymphatic sac was measured using the LAMMA technique. The K/Na ratio in the epithelial cells decreased after ethacrynic acid injection (60 mg/kg i.v.). These findings suggest that chloride in the endolymphatic sac is actively transported inward and outward.

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References

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