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. 1983 Mar-Apr;46(2):248-50.
doi: 10.1021/np50026a020.

Plant anticancer agents. XXVI. Constituents of Peddiea fischeri

S S Handa, A D Kinghorn, G A Cordell, N R Farnsworth

Plant anticancer agents. XXVI. Constituents of Peddiea fischeri

S S Handa et al. J Nat Prod. 1983 Mar-Apr.

Abstract

The in vitro P-388 lymphocytic leukemia activity of the chloroform-soluble fraction of the roots of Peddiea fischeri (Thymelaceaceae) was found to be due principally to the quinone 2,6-dimethoxybenzoquinone (2,6-DMBQ), and to a lesser extent the two coumarins daphnoretin and umbelliferone. This is the first report of the occurrence of 2,6-DMBQ in the family Thymelaeaceae. The occurrence of 2,6-DMBQ in higher plants is reviewed.

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