[Induction of postural asymmetry in an intact recipient with an extract from the brain of a donor with such a syndrome]

Abstract

An attempt was made of a direct transfer to the recipient of postural asymmetry originating after the removal of half of the anterior lobe of the cerebellum in rats. Postural asymmetry of the hind limbs proved to develop in spinal rats after subdural injection of brain extracts of the pathological donors below the spinal section level. Specificity of this asymmetry depending on the side of the cerebellar lesion was shown. The type of the recipient's asymmetry repeated the donor's asymmetry exactly. The brain extracts of control animals produced no asymmetry in the recipients. Additional evidence of the peptide nature of the factor stimulating postural asymmetry development was obtained: pronase inactivated the active brain extract.