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. 1983 Sep 2;221(4614):969-71.
doi: 10.1126/science.6879197.

Haloperidol-induced plasticity of axon terminals in rat substantia nigra

F M Benes, P A Paskevich, V B Domesick

Haloperidol-induced plasticity of axon terminals in rat substantia nigra

F M Benes et al. Science. .

Abstract

An electron micrographic morphometric analysis of nerve endings in substantia nigra of rats repeatedly treated with haloperidol was performed. Although most parameters showed no difference, drug-treated animals exhibited a significant shift in the distribution of relative numbers of axon terminals, suggesting neuroleptic-induced axon-collateral sprouting.

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