doi: 10.1016/0006-8993(83)91382-3.
Uptake of adenosine into cultured cerebral endothelium
- PMID: 6883117
- DOI: 10.1016/0006-8993(83)91382-3
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Uptake of adenosine into cultured cerebral endothelium
Brain Res.
.
Abstract
Adenosine uptake by cultured cerebral endothelium is a carrier-mediated process. The Km value for adenosine uptake is 5.0 microM and the vmax is 1.15 nmol/min/mg cell protein. The uptake system is inhibited by the adenosine analog 2-chloroadenosine at low adenosine concentrations. The results prove the existence of a nucleoside transport system associated with cerebral capillary endothelium.
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