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. 1983 Aug 22;160(1-2):98-100.
doi: 10.1016/0014-5793(83)80944-2.

The phorbol ester TPA increases the affinity of exocytosis for calcium in 'leaky' adrenal medullary cells

Free article

The phorbol ester TPA increases the affinity of exocytosis for calcium in 'leaky' adrenal medullary cells

D E Knight et al. FEBS Lett. .
Free article

Abstract

Exposure of 'leaky' bovine adrenal medullary cells to the phorbol ester TPA causes a shift in the calcium-activation curve to lower calcium concentrations without altering the levels of secretion at the extremes of the activation curve. These results are consistent with a role for protein kinase C in exocytosis.

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