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Case Reports
. 1982;62(3):271-6.
doi: 10.1007/BF00333535.

Translocation(X;Y)(p22.33;p11.2) in XX males: etiology of male phenotype

R E Magenis, M J Webb, R S McKean, D Tomar, L J Allen, H Kammer, D L Van Dyke, E Lovrien
Case Reports

Translocation(X;Y)(p22.33;p11.2) in XX males: etiology of male phenotype

R E Magenis et al. Hum Genet. 1982.

Abstract

Analysis of G-banded prometaphase chromosomes from three XX males revealed extra bands on the distal end of one X short arm. These bands were similar both in size and staining properties to the distal Y short arm of their fathers (in the two cases examined) and also to other chromosomally normal males. The extra material on the abnormal X chromosomes was not C- or G-11 positive in the two cases examined, suggesting that the proximal Y long arm was not present. Previous karyotype-phenotype correlations with structurally altered Y chromosomes provided evidence for localization of male determinants on the Y short arm. The present findings in XX males provide support for more precise localization, to bands p11.2 leads to pter of Y short arm.

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References

    1. Lancet. 1974 Jun 15;1(7868):1223 - PubMed
    1. J Med Genet. 1974 Dec;11(4):403-6 - PubMed
    1. Exp Cell Res. 1976 Oct 1;102(1):85-94 - PubMed
    1. Hum Genet. 1981;58(1):105-16 - PubMed
    1. Lancet. 1981 Aug 1;2(8240):255-6 - PubMed

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