The effect of anti-eosinophil serum on skin histamine replenishment following passive cutaneous anaphylaxis in the guinea-pig
- PMID: 68922
- PMCID: PMC1445240
The effect of anti-eosinophil serum on skin histamine replenishment following passive cutaneous anaphylaxis in the guinea-pig
Abstract
Depletion of eosinophils by an antieosinophil serum resulted in the inhibition of histamine reaccumulation into guinea-pig skin sites following IgG1-mediated passive cutaneous anaphylaxis. This suggests that eosinophils may have a regulatory role in the repair mechanism which follows immediate-type hypersensitivity reactions.
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