Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jul;33(1):101-7.

Detection and molecular characterization of the thymus-brain antigen in human brain

R Arndt, R Stark, H G Thiele

Detection and molecular characterization of the thymus-brain antigen in human brain

R Arndt et al. Immunology. 1977 Jul.

Abstract

Anti-human brain sera were found to contain antibodies reacting with determinants present on murine thymocyte plasma membranes. This determinant is borne by the thymocyte-brain antigen of mouse thymocytes. The non species-specific determinant of the thymocyte-brain system is detectable on the thymocyte-brain antigen of human and mouse brain in comparable amounts. In contrast to these findings, the allogenic Thy-1 and the species-specific determinant of this system were only found on the thymocyte-brain antigen of mouse brain but not on the corresponding antigen of human brain. The molecular weight, Stokes radius and diffusion coefficient of the thymocyte-brain antigen of human and mouse brain are in good accordance with the data estimated for the corresponding antigen of murine thymocytes.

PubMed Disclaimer

References

    1. Proc Soc Exp Biol Med. 1975 Apr;148(4):1126-31 - PubMed
    1. J Immunol. 1976 Apr;116(4):1041-4 - PubMed
    1. J Biol Chem. 1963 Feb;238:622-7 - PubMed
    1. J Exp Med. 1964 Sep 1;120:413-33 - PubMed
    1. J Exp Med. 1972 Nov 1;136(5):1054-62 - PubMed

LinkOut - more resources