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. 1980 Oct;23(10):1134-6.
doi: 10.1021/jm00184a014.

Ivermectin, a new broad-spectrum antiparasitic agent

J C Chabala, H Mrozik, R L Tolman, P Eskola, A Lusi, L H Peterson, M F Woods, M H Fisher, W C Campbell, J R Egerton, D A Ostlind

Ivermectin, a new broad-spectrum antiparasitic agent

J C Chabala et al. J Med Chem. 1980 Oct.

Abstract

22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.

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