Myosin phosphorylation and the cross-bridge cycle in arterial smooth muscle
- PMID: 6893872
- DOI: 10.1126/science.6893872
Myosin phosphorylation and the cross-bridge cycle in arterial smooth muscle
Abstract
Phosphorylation of the 20,000-dalton light chain of myosin is closely correlated with cross-bridge cycling in arterial smooth muscle. Evidence is presented that dephosphorylation can produce an attached, noncycling cross-bridge (latch-bridge) which is responsible for the high economy of force maintenance in this tissue.
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