Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Aug;21(2):655-8.
doi: 10.1128/iai.21.2.655-658.1978.

Disruption of the permeability barrier (zonula occludens) between intestinal epithelial cells by lethal doses of endotoxin

R I Walker, M J Porvaznik

Disruption of the permeability barrier (zonula occludens) between intestinal epithelial cells by lethal doses of endotoxin

R I Walker et al. Infect Immun. 1978 Aug.

Abstract

A freeze-fracture technique was used to examine the most apical intercellular junctional complex between intestinal epithelial cells (the tight or occluding junction) in mice after challenge with endotoxin. Some of these junctions were disrupted after challenge and may be a site for leakage of microbial agents from the lumen.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Proc Soc Exp Biol Med. 1959 Jan;100(1):65-8 - PubMed
    1. J Clin Invest. 1958 Mar;37(3):441-57 - PubMed
    1. Lancet. 1972 Jun 24;1(7765):1381-5 - PubMed
    1. Lancet. 1972 Jul 22;2(7769):181 - PubMed
    1. Science. 1975 Oct 3;190(4209):54-6 - PubMed

LinkOut - more resources